BINDSの支援を受けた研究成果（論文）
Takayuki Kato , Fumiaki Makino , Takanori Nakane , Naoya Terahara , Takeshi Kaneko , Yuko Shimizu , Sohei Motoki , Isamu Ishikawa, Koji Yonekura, and Keiichi Namba (2020)
Structure of the native supercoiled flagellar hook as a universal joint Microsc. Microanal.
25
998-999 DOI: DOI: https://doi.org/10.1017/S1431927619005725
Takayuki Kato, Fumiaki Makino, Tomoko Miyata, Péter Horváth & Keiichi Namba (2019)
Structure of the native supercoiled flagellar hook as a universal joint Nat. commun..
10
DOI:https://doi.org/10.1038/s41467-019-13252-9
Yurika Yamada, Keiichi Namba & Takashi Fujii (2020)
Cardiac muscle thin filament structures reveal calcium regulatory mechanism Nat. commun..
11
DOI:https://doi.org/10.1038/s41467-019-14008-1
Hiroyuki Terashima,Chinatsu Tatsumi,Akihiro Kawamoto,Keiichi Namba,Tohru Minamino, andKatsumi Imada (2020)
In Vitro Autonomous Construction of the Flagellar Axial Structure in Inverted Membrane Vesicles Biomolecules.
10
:1,
DOI:https://doi.org/10.3390/biom10010126
Masahiro Hiraizumi, Keitaro Yamashita, Tomohiro Nishizawa, Osamu Nureki (2019)
Cryo-EM structures capture the transport cycle of the P4-ATPase flippase Science .
365
1149-1155 DOI:https://doi.org/10.1126/science.aay3353
Yuhei Araiso, Akihisa Tsutsumi, Jian Qiu, Kenichiro Imai, Takuya Shiota, Jiyao Song, Caroline Lindau, Lena-Sophie Wenz, Haruka Sakaue, Kaori Yunoki, Shin Kawano, Junko Suzuki, Marilena Wischnewski, Conny Schütze, Hirotaka Ariyama, Toshio Ando, Thomas Becker, Trevor Lithgow, Nils Wiedemann, Nikolaus Pfanner, Masahide Kikkawa & Toshiya Endo (2019)
Structure of the mitochondrial import gate reveals distinct preprotein paths Nature.
575
395-401 DOI:https://doi.org/10.1038/s41586-019-1680-7
Jumpei Morimoto*Yasuhiro FukudaDaisuke KurodaTakumu WatanabeFumihiko YoshidaMizue AsadaToshikazu NakamuraAkinobu SenooSatoru NagatoishiKouhei TsumotoShinsuke Sando (2019)
A Peptoid with Extended Shape in Water J. Am. Chem. Soc..
141
:37,
14612-14623 DOI:doi: 10.1021/jacs.9b04371
Kouhei Yoshida Satoru Nagatoishi Daisuke Kuroda Nanao Suzuki Takeshi Murata Kouhei Tsumoto (2019)
Phospholipid Membrane Fluidity Alters Ligand Binding Activity of a G Protein-Co biochemistry.
58
504-508 DOI:doi: 10.1021/acs.biochem.8b01194
Kazuhiro Nishiyama, Takuro Numaga‐Tomita, Yasuyuki Fujimoto, Tomohiro Tanaka, Chiemi Toyama, Akiyuki Nishimura, Tomohiro Yamashita, Naoya Matsunaga, Satoru Koyanagi, Yasu‐Taka Azuma, Yuko Ibuki, Koji Uchida, Shigehiro Ohdo, |Motohiro Nishida (2019)
Ibudilast attenuates doxorubicin‐induced cytotoxicity bysuppressing formation of TRPC3 channel and NADPH oxidase2 protein complexes Br J Pharmacol..
176
3723-3738 DOI:doi: 10.1111/bph.14777
Takuya Yokoyama, Masaki Yukuhiro, Yuka Iwasaki, Chika Tanaka, Kazunari Sankoda, Risa Fujiwara, Atsushi Shibuta, Taishi Higashi, Keiichi Motoyama, Hidetoshi Arima, Kazumasa Yoshida, Nozomi Sugimoto, Hiroyuki Morimoto, Hidetaka Kosako, Takashi Ohshima & Masatoshi Fujita (2019)
Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10 SCIENTIFIC REPORTS.
9
DOI:doi: 10.1038/s41598-019-53259-2
Tatsuhiro Igawa, Shuhei Kishikawa, Yoshito Abe, Tomohiro Yamashita, Saki Nagai, Mitsunori Shiroishi, Chinatsu Shinozaki, Hiroyuki Tanaka, Hidetoshi Tozaki-Saitoh, Makoto Tsuda, Kazuhide Inoue, and Tadashi Ueda (2019)
Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure Purinergic Signal.
15
:1,
27-35 DOI:doi: 10.1007/s11302-019-09646-5
Shota Yamamoto Tomohiro Yamashita Mayu Ito Jose M.M. Caaveiro Nobuaki Egashira Hidetoshi Tozaki‐Saitoh Makoto Tsuda (2019)
New pharmacological effect of fulvestrant to prevent oxaliplatin‐induced neurodegeneration and mechanical allodynia in rats Int. J. cancer.
145
:8,
2017-2113 DOI:doi: 10.1002/ijc.32043
Shindo N, Fuchida H Sato H, Watari K, Shibata T, Kuwata K, Miura C, Okamoto K, Hatsuyama Y, Tokunag K, Sakamoto S, Morimoto S, Abe Y, Shiroishi M, Caaveiro JMM, Ueda T, Tamura T, Matsunaga N, Nakao T, Koyanagi S, Ohdo S, Yamaguchi Y, Hamachi I, Ono M, Ojida A. (2019)
Selective and Reversible Modification of Kinase Cysteines with Chlorofluoroacetamides. Nature Chem Biol.
15
250-258 DOI:doi: 0.1038/s41589-018-0204-3
Naoya Matsunaga, Yuya Yoshida, Naoki Kitajou, Akira Shiraishi, Naoki Kusunose, Satoru Koyanagi, Shigehiro Ohdo (2019)
Microcurrent stimulation activates the circadian machinery in mice Biochemical and Biophysical Research Communications.
513
:2,
293-299 DOI:doi: 10.1016/j.bbrc.2019.02.022
Rina Maeda, Shinsuke Sato, Shunsuke Obata, Tomo Ohno, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama (2019)
Molecular Characteristics of DNA-Alkylating PI Polyamides Targeting RUNX Transcription Factors J. Am. Chem. Soc..
141
:10,
4257-4263 DOI:doi: 10.1021/jacs.8b08813
Riyo Maruki Imamura, Kazuo Kumagai, Hirofumi Nakano,Takayoshi Okabe, Tetsuo Nagano, and Hirotatsu Kojima (2019)
Inexpensive High-Throughput Screening of Kinase Inhibitors Using One-Step Enzyme-Coupled Fluorescence Assay SLAS Discovery.
24
:243,
284-294 DOI:DOI: 10.1177/2472555218810139
MasatoOgura, HaruhisaKikuchi, NorshalenaShakespear, ToshiyukiSuzuki, JunkoYamaki, Miwako K.Homma, YoshiteruOshima, YoshimiHomma (2019)
Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK4 Biochem Pharmacol..
162
109-122 DOI:doi: 10.1016/j.bcp.2018.10.008.
Koji Sato, Naonori Kumagai and Norio Suzuki (2019)
Alteration of the DNA Methylation Signature of Renal Erythropoietin-Producing Cells Governs the Sensitivity to Drugs Targeting the Hypoxia-Response Pathway in Kidney Disease Progression Front. Genet.
DOI:doi: 10.3389/fgene.2019.01134
Kosuke Ohsawa, Masato Sugai, Linnan Zhang, Yuichi Masuda, Masahito Yoshida, and Takayuki Doi (2019)
Total Synthesis and Structural Revision of Cyclotetrapeptide Asperterrestide A J.Org Chem.
84
6765-6779 DOI:doi: 10.1021/acs.joc.9b00526
Masahito Yoshida Kenta Adachi Hayato Murase Hiroshi Nakagawa Takayuki Doi (2019)
Parallel Synthesis and Biological Evaluation of Destruxin E Analogs Modified with a Side Chain in the α‐Hydroxycarboxylic Acid Moiety Eur.J. Org.Chem..
84
1669-1676 DOI:Eur.J. Org.Chem.
Hiroko Izumi-Nakaseko, Masachika Fujiyoshi, Mihoko Hagiwara-Nagasawa, Ai Goto, Koki Chiba, Ryuichi Kambayashi, Atsuhiko T. Naito, Kentaro Ando, Yasunari Kanda, Itsuko Ishii, Atsushi Sugiyama (2019)
Dasatinib can Impair Left Ventricular Mechanical Function But May Lack Proarrhythmic Effect: A Proposal of Non-clinical Guidance for Predicting Clinical Cardiovascular Adverse Events of Tyrosine Kinase Inhibitors Cardiovasc Toxicol. .
1-13 DOI:doi: 10.1007/s12012-019-09538-5
Tomii K, Santos HJ, Nozaki T (2019)
Genome-Wide Analysis of Known and Potential Tetraspanins in Entamoeba histolytica Genes.
10
:11,
DOI:https://doi.org/10.3390/genes10110885
Kazuhisa Miyake, Ayuko Sakane, YukoTsuchiya, Ikuko Sagawa, YokoTomida, Jiro Kasahara, Issei Imoto, ShioWatanabe, Daisuke Higo, Kenji Mizuguchi & Takuya Sasaki (2019)
Actin Cytoskeletal Reorganization Function of JRAB/MICAL-L2 Is Fine-tuned by Intramolecular Interaction between First LIM Zinc Finger and C-terminal Coiled-coil Domains SCIENTIFIC REPORTS.
9
DOI:doi:10.1038/s41598-019-49232-8
Herbert J. Santos Kenichiro Imai Takashi Makiuchi Kentaro Tomii Paul Horton Akira Nozawa Kenta Okada Yuzuru Tozawa Tomoyoshi Nozaki (2019)
Novel lineage‐specific transmembrane β‐barrel proteins in the endoplasmic reticulum of Entamoeba histolytica The FEBS Journal.
286
:17,
3416-3432 DOI:https://doi.org/10.1111/febs.14870
Yuko Tsuchiya, Kei Taneishi, and Yasushige Yonezawa (2019)
Autoencoder-Based Detection of Dynamic Allostery Triggered by Ligand Binding Based on Molecular Dynamics J.Chem.Inf.Model..
59
:9,
4043-4051 DOI:https://doi.org/10.1021/acs.jcim.9b00426
Yoshinori Fukasawa & Kentaro Tomii (2019)
Accurate Classification of Biological and non-Biological Interfaces in Protein Crystal Structures using Subtle Covariation Signals SCIENTIFIC REPORTS.
9
DOI:https://doi.org/10.1038/s41598-019-48913-8
Shuntaro Chiba, Masahito Ohue, Anastasiia Gryniukova Petro Borysko, Sergey Zozulya, Nobuaki Yasuo, Ryunosuke Yoshino, Kazuyoshi Ikeda, Woong-Hee Shin, Daisuke Kihara, Mitsuo Iwadate, Hideaki Umeyama, Takaaki Ichikawa, Reiji Teramoto, Kun-Yi Hsin, Vipul Gupta, Hiroaki Kitano, Mika Sakamoto, Akiko Higuchi, Nobuaki Miura, Kei Yura, Masahiro Mochizuki, Chandrasekaran Ramakrishnan, A. Mary Thangakani, D. Velmurugan, M. Michael Gromiha, Itsuo Nakane, Nanako Uchida, Hayase Hakariya, Modong Tan, Hironori K. Nakamura, Shogo D. Suzuki, Tomoki Ito, Masahiro Kawatani, Kentaroh Kudoh, Sakurako Takashina, Kazuki Z. Yamamoto, Yoshitaka Moriwaki, Keita Oda, Daisuke Kobayashi, Tatsuya Okuno, Shintaro Minami, George Chikenji, Philip Prathipati, Chioko Nagao, Attayeb Mohsen, Mari Ito, Kenji Mizuguchi, Teruki Honma, Takashi Ishida, Takatsugu Hirokawa, Yutaka Akiyama, Masakazu Sekijima (2020)
A prospective compound screening contest identified broader inhibitors for Sirtuin 1
SCIENTIFIC REPORTS.
:9,
19585- DOI:10.1038/s41598-019-55069-y
Tatsuya Furuichi, Manami Tsukamoto, Masaki Saito, Yuriko Sato, Nobuyasu Oiji, Kazuhiro Yagami, Ryutaro Fukumura, Yoichi Gondo, Long Guo, Shiro Ikegawa, Yu Yamamori, Kentaro Tomii (2019)
Crim1C140S mutant mice reveal the importance of cysteine 140 in the internal region 1 of CRIM1 for its physiological functions
Mammalian Genome.
11-12
:30,
329-338 DOI:https://doi.org/10.1007/s00335-019-09822-3
Masashi Tachibana, Nobumasa Watanabe4, Yuzo Koda, Yukako Oya, Osamu Kaminuma, Kazufumi Katayama, Zifei Fan, Fuminori Sakurai, Kenji Kawabata5, Takachika Hiroi4, Hiroyuki Mizuguchi (2019)
Ablation of IL-17A leads to severe colitis in IL-10-deficient mice: implications of myeloid-derived suppressor cells and NO production
International immunology.
1-46 DOI:https://doi.org/10.1093/intimm/dxz076
Yasumitsu Sakamoto, Yoshiyuki Suzuki, Akihiro Nakamura, Yurie Watanabe, Mizuki Sekiya, Saori Roppongi, Chisato Kushibiki, Ippei Iizuka, Osamu Tani, Hitoshi Sakashita, Koji Inaka, Hiroaki Tanaka, Mitsugu Yamada, Kazunori Ohta, Nobuyuki Honma, Yosuke Shida, Wataru Ogasawara, Mayumi Nakanishi-Matsui, Takamasa Nonaka, Hiroaki Gouda , Nobutada Tanaka (2019)
Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase
Scientific Reports.
:in press,
DOI:https://doi.org/10.1038/s41598-019-49984-3
Saori Roppongi, Yoshiyuki Suzuki, Chika Tateoka, Mayu Fujimoto, Saori Morisawa, Ippei Iizuka, Akihiro Nakamura, Nobuyuki Honma, Yosuke Shida, Wataru Ogasawara, Nobutada Tanaka, Yasumitsu Sakamoto,Takamasa Nonaka (2019)
Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues
Scientific Reports.
:in press,
DOI:DOI:10.1038/s41598-018-21056-y
Yoshiaki Shimazu, Kensuke Tono, Tomoyuki Tanaka, Yasuaki Yamanaka, Takanori Nakane, Chihiro Mori, Kanako Terakado Kimura, Takaaki Fujiwara, Michihiro Sugahara, Rie Tanaka, R. Bruce Doak, Tatsuro Shimamura, So Iwata, Eriko Nango, and Makina Yabashi (2019)
High-viscosity sample-injection device for serial femtosecond crystallography at atmospheric pressure
Journal of Applied Crystallography.
52
1280-1288 DOI:https://doi.org/10.1107/S1600576719012846
Takahisa Taniguchi , Nozomi Saito , Ryohei Doi , Arato Kimoto , Naoyuki Hoshiya , Katsumasa Fujiki , Satoshi Shuto , Hiromichi Fujioka , Mitsuhiro Arisawa , and Yoshihiro Sato (2019)
Nickel Nanoparticle-Catalyzed Carboxylation of Unsaturated Hydrocarbon with CO2 Using Sulfur-Modified Au-Supported Nickel Material
chemistry letters.
48
:11,
1406-1409 DOI:https://doi.org/10.1246/cl.190650
Jyuan C. Sanchez, Melissa Carrillo, Suraj Pandey, Moraima Noda, Luis Aldama, Denisse Feliz, Elin Claesson, Weixiao Yuan Wahlgren, Gregory Tracy, Phu Duong, Angela C. Nugent, Andrew Field, Vukica Šrajer, Christopher Kupitz, So Iwata, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Luo Fangjia, Kensuke Tono, Shigeki Owada, Sebastian Westenhoff, Marius Schmidt, and Emina A. Stojković (2019)
High-resolution crystal structures of a myxobacterial phytochrome at cryo and room temperatures
Structural Dynamics .
54701
:6,
1-9 DOI:https://doi.org/10.1063/1.5120527
YukiKanado, YuyaTsurudome, YujiOmata, SaiYasukochi, NaokiKusunose, TakahiroAkamine, NaoyaMatsunaga, SatoruKoyanagi, ShigehiroOhdo (2019)
Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs
Biochemical and Biophysical Research Communications.
519
:3,
613-619 DOI:https://doi.org/10.1016/j.bbrc.2019.09.021
Hideo Fukuhara, Yuri Ito, Miyuki Sako, Mizuho Kajikawa, Koki Yoshida, Fumio Seki, Mwila Hilton Mwaba, Takao Hashiguchi, Masa-aki Higashibata, Toyoyuki Ose, Kimiko Kuroki, Makoto Takeda and Katsumi Maenaka (2019)
Specificity of Morbillivirus Hemagglutinins to Recognize SLAM of Different Species
Viruses.
11
:8,
DOI:https://doi.org/10.3390/v11080761
Hirofumi Tsujino,Tadayuki Uno,Taku Yamashita,Masafumi Katsuda,Kazuki Takada,Takeshi Saiki,Shotaro Maeda,Akira Takagi,Shigeaki Masuda,Yasuhiko Kawano,Kanji Meguro,Shuji Akai (2019)
Correlation of indoleamine-2,3-dioxigenase 1 inhibitory activity of 4,6-disubstituted indazole derivatives and their heme binding affinity
Bioorganic & Medicinal Chemistry Letters.
29
:19,
DOI:https://doi.org/10.1016/j.bmcl.2019.08.011
HiroyukiMiyachi, TomohiroYuzuriha, RyotaroTabata, SyoheiFukuda, KazutoNunomura, BangzhongLin, TadayukiKobayashi, KenjiIshimoto, TakefumiDoi, KeisukeTachibana (2019)
Structural development of 1H-pyrazolo-[3,4-b]pyridine-4-carboxylic acid derivatives as human peroxisome proliferator-activated receptor alpha (PPARα)-selective agonists
Bioorganic & Medicinal Chemistry Letters.
29
:16,
2124-2128 DOI:https://doi.org/10.1016/j.bmcl.2019.06.062
Yosuke Sakata, Kosuke Yabunaka, Yuko Kobayashi, Hirohisa Omiya, Naoki Umezawa , Hye-Sook Kim, Yusuke Wataya, Yoshimi Tomita, Yosuke Hisamatsu, Nobuki Kato, Hirokazu Yagi, Tadashi Satoh, Koichi Kato¶, Haruto Ishikawa, and Tsunehiko Higuchi (2019)
Potent Antimalarial Activity of Two Arenes Linked with Triamine Designed To Have Multiple Interactions with Heme
ACS Medicinal. Chemistry. Letters.
9
:10,
980-985 DOI:10.1021/acsmedchemlett.8b00222
Taito Matsuda, Takashi Irie, Shutaro Katsurabayashi, Yoshinori Hayashi, Tatsuya Nagai, Nobuhiko Hamazaki, Aliya Mari D Adefuin, Fumihito Miura, Takashi Ito, Hiroshi Kimura, Katsuhiko Shirahige, Tadayuki Takeda, Katsunori Iwasaki, Takuya Imamura, Kinichi Nakashima (2019)
Pioneer factor NeuroD1 rearranges transcriptional and epigenetic profiles to execute microglia-neuron conversion.
Neuron.
101
:3,
472-485 DOI:10.1016/j.neuron.2018.12.010. PMID:30638745
